Applied Physics Laboratory (APL) is a research laboratory at the Faculty of Electronic Engineering, University of Niš, Serbia, that connects the conventionally considered "engineering" and "pure physics" disciplines. Since the interests of both engineering and pure physics cover fields that overlap, a definitive dividing line cannot be drawn between them. Situated at Faculty of Electronic Engineering, APL has been naturally oriented to conduct the research in the applied physics field.

APL researchers have achieved world-class research results, with over 100 publications in peer reviewed international scientific journals and numerous international and national conference presentations.

In period 2008-2012, the FP7 - RADDOS project (EU Center of Excellence call) was realized in APL. The local coordinator was Prof. Goran Ristić, Head of APL.

In period 2011 – present, the interdisciplinary national project funded by the Serbian Ministry of Education, Science and Technological Development has been realized in APL. The coordinator is Prof. Goran Ristić, Head of APL.

In period 2019 - present, the Horizon 2020 - ELICSIR project (Twinning call) has been realized in APL. The coordinator is Prof. Goran Ristić, Head of APL.